Key Takeaways Kratom is not a treatment for benzodiazepine withdrawal, and I recommend avoiding it. Kratom contains mitragynine and related alkaloids that act on the mu opioid receptor, so it…
Key Takeaways Benzodiazepine withdrawal insomnia comes from disrupted signaling of gamma-aminobutyric acid (GABA), the brain's main calming chemical, which leaves the nervous system too activated to let sleep take hold.…
Key Takeaways Opioid withdrawal usually lasts at least a week, reaches its peak around the third day, and becomes tolerable after a week or two, though cravings can continue for…
What is safe to take with naltrexone, and what is not safe to take with naltrexone? Naltrexone is an opioid antagonist drug, which means that it blocks opioid receptors. It…
What exactly is iatrogenic akathisia? Akathisia is a movement disorder, possibly related to subcortical excitation, that is experienced as a feeling of inner restlessness. Some people who suffer from akathisia…
Is buprenorphine the same as methadone? We have been in the midst of an opioid overdose epidemic for many years now. While there are many approaches to treating opioid addiction,…
Is breaking the cycle of drug addiction possible? How can we stop the cycle of addiction? Why is it that people who develop a substance use disorder enter an addictive…
Should medical cannabis be avoided when starting Suboxone? There is some confusion over the use of marijuana during medication assisted treatment for opioid use disorder. People who are starting Suboxone…
Bupe, Buse, Sobos, Subs, Stops, Strips, Subox, Sabaxin, and Subs. What is Subox, and why is it showing up in discussions about opioid dependence treatment? Are all of these unusual…
Is there a difference in safety between a low dose naltrexone pregnancy and naltrexone in pregnancy with the standard 25 mg or 50 mg dose? Naltrexone HCL is a drug…